Endocrine Abstracts

Patients on long term prednisolone therapy have suppression of their hypothalamo-pituitary-adrenal (HPA) axis. The short synacthen test (SST) is routinely employed to assess the viability of the HPA axis. However, as this test examines only adrenal function it may fail to identify those patients with secondary adrenal insufficiency. The overnight metyrapone test (OMT) may be a better test as it examines the whole HPA axis.We have compared the responses t...